The modern rhythm of life, Stress, polluted air and frequent colds undermine the immune system, Especially in people, prone to chronic respiratory diseases. Various immunomodulatory drugs are used to support immunity and reduce the risk of recurrent infections. One of these means is Ismigen - sublingual tablets, which every year gain more and more trust among doctors and patients.
What is Ismigen

Ismigen (Same) is an immunomodulatory drug of bacterial origin, available in the form of sublingual tablets. Its main task is to strengthen the body's immune defense, increase resistance to respiratory tract infections and reduce the frequency of exacerbations of chronic diseases of the ENT organs.
Ismigen belongs to the group of bacterial lysates - special preparations, containing destroyed cells of pathogenic microorganisms. These microbial fragments do not cause disease, but they stimulate the immune system to “turn on” and form a response, as if it were a real infection. It is a kind of “vaccine” for the immune system.
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Composition of the drug
The main active ingredient is bacteria lysate, including destroyed fragments of the following pathogens:
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Streptococcus pneumoniae
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Haemophilus influenzae
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Klebsiella pneumoniae
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Staphylococcus aureus
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Streptococcus pyogenes
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Moraxella catarrhalis
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and others
This composition was selected taking into account the fact, what bacteria most often cause respiratory tract diseases. Tablets are designed to be dissolved under the tongue, which ensures rapid penetration of the active substance into the lymphoid tissue and activation of local immunity.
Mechanism of action
Ismigen activates innate and acquired immunity. After resorption, bacterial lysates interact with immune cells of the mucous membrane of the mouth and pharynx, which leads to:
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activation of macrophages and lymphocytes,
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production of interferons and other immune proteins,
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strengthening local respiratory protection,
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formation of immune system memory (upon repeated contact with the pathogen, the body reacts faster).
This makes Ismigen especially effective for chronic and often recurrent infections.
Indications for use
Ismigen is recommended for prevention and as part of complex treatment:
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chronic bronchitis,
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tonsillitis,
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pharyngitis,
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laryngitis,
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sinusitis,
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rhinitis,
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otitis,
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other diseases of the upper and lower respiratory tract.
The drug is also suitable for frequently ill children, people with reduced immunity and patients, who are recovering from prolonged infections.
Who is Ismigen especially useful for?
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Children of school and preschool age, those who often suffer from ARVI
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Adults with chronic diseases of the ENT organs
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People, working in teams (school, offices, medical institutions)
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For patients, who are prone to frequent relapses of sore throat, bronchitis and sinusitis
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For patients during the off-season or epidemics
Advantages of the sublingual form
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Fast and complete absorption
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Convenience of taking without water
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Local effect on mucosal immune cells
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Minimum side effects
The sublingual form allows the drug not to pass through the stomach and liver, keeping you active and reducing stress on your digestive system.
Recommendations for use
Typically the course of treatment is 10 days, then a 20 day break, after which the course is repeated. Often prescribed according to the following scheme: 1 tablet in the morning on an empty stomach, without chewing, holding under the tongue until completely dissolved.
It is important to follow the doctor’s recommendations and not interrupt the course - the effectiveness of the drug depends on the regularity of use.
Possible side effects and contraindications
Ismigen, as a rule, well tolerated. Possible reactions:
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individual intolerance to the components,
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mild itching or irritation in the mouth,
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in rare cases - gastrointestinal discomfort.
Contraindicated:
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younger children 3 years,
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people with hypersensitivity to components,
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for acute autoimmune diseases (as prescribed by a doctor).
During pregnancy and lactation, the drug should be used with caution and under the supervision of a specialist..
Comparison with analogues
There are also other preparations on the market based on bacterial lysates - for example, Broncho-Munal, Imudon, Ribomunil. However, Ismigen compares favorably:
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Reception form - sublingual tablets instead of capsules or sprays
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Wide composition - covers a larger number of pathogens
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Quick action — activates the immune system from the first days of use
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No systemic side effects
Useful tips
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Start taking Ismigen early, 2–3 weeks before the period of high incidence.
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Don't interrupt the course - this reduces efficiency.
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Combine with general strengthening measures: hardening, vitamins, balanced diet.
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Consult your doctor, especially in the presence of chronic diseases.
We will summarize
Ismigen is a modern solution for the prevention and complex treatment of respiratory tract infections. The drug helps strengthen the body's natural defenses and reduce the risk of recurrent diseases. Thanks to its comfortable sublingual shape, minimal side effects and proven effectiveness, it is widely used both in pediatric, and in adult practice.
If you or your child are often sick, suffer from chronic inflammation, or want to strengthen your immune system before the cold season - Ismigen can become a reliable assistant in this process.










